Monopolar Spindle 1 Kinase (MPS1/TTK) mRNA Expression is Associated with Earlier Development of Clinical Symptoms, Tumor Aggressiveness and Survival of Glioma Patients

Inhibition of the protein kinase MPS1, a mitotic spindle-checkpoint regulator, reinforces the effects of multiple therapies against glioblastoma multiforme (GBM) in experimental settings. We analyzed MPS1 mRNA-expression in gliomas WHO grade II, III and in clinical subgroups of GBM. Data were obtain...

Descripción completa

Detalles Bibliográficos
Autores principales: Kessler, Almuth F., Feldheim, Jonas, Schmitt, Dominik, Feldheim, Julia J., Monoranu, Camelia M., Ernestus, Ralf-Ingo, Löhr, Mario, Hagemann, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399822/
https://www.ncbi.nlm.nih.gov/pubmed/32635204
http://dx.doi.org/10.3390/biomedicines8070192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399822/
https://www.ncbi.nlm.nih.gov/pubmed/32635204
http://dx.doi.org/10.3390/biomedicines8070192

Ejemplares similares