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HDX-MS: An Analytical Tool to Capture Protein Motion in Action

Virtually all protein functions in the cell, including pathogenic processes, require coordinated motion of atoms or domains, i.e., conformational dynamics. Understanding protein dynamics is therefore critical both for drug development and to learn about the underlying molecular causes of many diseas...

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Detalles Bibliográficos
Autores principales: Narang, Dominic, Lento, Cristina, J. Wilson, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399943/
https://www.ncbi.nlm.nih.gov/pubmed/32709043
http://dx.doi.org/10.3390/biomedicines8070224