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Knockdown of m6A methyltransferase METTL3 in gastric cancer cells results in suppression of cell proliferation

N6-methyladenosine (m6A) RNA modification regulates multiple biological functions. Methyltransferase like 3 (METTL3), one of the major N6-methyltransferases, is highly expressed in gastric cancer, but its potential role in disease is unclear. The current study knocked out METTL3 (METTL3-KO) in human...

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Detalles Bibliográficos
Autores principales: Jiang, Li, Chen, Ting, Xiong, Li, Xu, Ji-Hao, Gong, Ai-Yu, Dai, Bin, Wu, Ganlin, Zhu, Kenny, Lu, Eugene, Mathy, Nicholas William, Chen, Xian-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400027/
https://www.ncbi.nlm.nih.gov/pubmed/32782536
http://dx.doi.org/10.3892/ol.2020.11794