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Knockdown of m6A methyltransferase METTL3 in gastric cancer cells results in suppression of cell proliferation
N6-methyladenosine (m6A) RNA modification regulates multiple biological functions. Methyltransferase like 3 (METTL3), one of the major N6-methyltransferases, is highly expressed in gastric cancer, but its potential role in disease is unclear. The current study knocked out METTL3 (METTL3-KO) in human...
Autores principales: | Jiang, Li, Chen, Ting, Xiong, Li, Xu, Ji-Hao, Gong, Ai-Yu, Dai, Bin, Wu, Ganlin, Zhu, Kenny, Lu, Eugene, Mathy, Nicholas William, Chen, Xian-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400027/ https://www.ncbi.nlm.nih.gov/pubmed/32782536 http://dx.doi.org/10.3892/ol.2020.11794 |
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