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The Nuclear Lamina: Protein Accumulation and Disease

Cellular health is reliant on proteostasis—the maintenance of protein levels regulated through multiple pathways modulating protein synthesis, degradation and clearance. Loss of proteostasis results in serious disease and is associated with aging. One proteinaceous structure underlying the nuclear e...

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Detalles Bibliográficos
Autores principales: Almendáriz-Palacios, Carla, Gillespie, Zoe E., Janzen, Matthew, Martinez, Valeria, Bridger, Joanna M., Harkness, Troy A. A., Mousseau, Darrell D., Eskiw, Christopher H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400325/
https://www.ncbi.nlm.nih.gov/pubmed/32630170
http://dx.doi.org/10.3390/biomedicines8070188