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The Nuclear Lamina: Protein Accumulation and Disease
Cellular health is reliant on proteostasis—the maintenance of protein levels regulated through multiple pathways modulating protein synthesis, degradation and clearance. Loss of proteostasis results in serious disease and is associated with aging. One proteinaceous structure underlying the nuclear e...
Autores principales: | Almendáriz-Palacios, Carla, Gillespie, Zoe E., Janzen, Matthew, Martinez, Valeria, Bridger, Joanna M., Harkness, Troy A. A., Mousseau, Darrell D., Eskiw, Christopher H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400325/ https://www.ncbi.nlm.nih.gov/pubmed/32630170 http://dx.doi.org/10.3390/biomedicines8070188 |
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