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Soy Isoflavone Genistein Impedes Cancer Stemness and Mesenchymal Transition in Head and Neck Cancer through Activating miR-34a/RTCB Axis

Genistein, a soy-derived phytoestrogen, has been shown to exhibit anti-neoplastic activities in various cancers. Nevertheless, its effects on the elimination of tumor-initiating cells of head and neck cancer (HNC-TICs) remain unclear. Here, we investigated the inhibitory effect of genistein on HNC-T...

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Detalles Bibliográficos
Autores principales: Hsieh, Pei-Ling, Liao, Yi-Wen, Hsieh, Chang-Wei, Chen, Pei-Ni, Yu, Cheng-Chia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400540/
https://www.ncbi.nlm.nih.gov/pubmed/32610494
http://dx.doi.org/10.3390/nu12071924