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Human pluripotent stem cell-derived cardiomyocytes as a target platform for paracrine protection by cardiac mesenchymal stromal cells

Ischemic heart disease remains the foremost cause of death globally, with survivors at risk for subsequent heart failure. Paradoxically, cell therapies to offset cardiomyocyte loss after ischemic injury improve long-term cardiac function despite a lack of durable engraftment. An evolving consensus,...

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Detalles Bibliográficos
Autores principales: Constantinou, Chrystalla, Miranda, Antonio M. A., Chaves, Patricia, Bellahcene, Mohamed, Massaia, Andrea, Cheng, Kevin, Samari, Sara, Rothery, Stephen M., Chandler, Anita M., Schwarz, Richard P., Harding, Sian E., Punjabi, Prakash, Schneider, Michael D., Noseda, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400574/
https://www.ncbi.nlm.nih.gov/pubmed/32747668
http://dx.doi.org/10.1038/s41598-020-69495-w