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Optimization of Molecular Dynamics Simulations of c-MYC(1-88)—An Intrinsically Disordered System

Many of the proteins involved in key cellular regulatory events contain extensive intrinsically disordered regions that are not readily amenable to conventional structure/function dissection. The oncoprotein c-MYC plays a key role in controlling cell proliferation and apoptosis and more than 70% of...

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Detalles Bibliográficos
Autores principales: Sullivan, Sandra S., Weinzierl, Robert O.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400636/
https://www.ncbi.nlm.nih.gov/pubmed/32664335
http://dx.doi.org/10.3390/life10070109