PSGL-1 inhibits HIV-1 infection by restricting actin dynamics and sequestering HIV envelope proteins

PSGL-1 has recently been identified as an HIV restriction factor that inhibits HIV DNA synthesis and more potently, virion infectivity. But the underlying mechanisms of these inhibitions are unknown. Here we show that PSGL-1 directly binds to cellular actin filaments (F-actin) to restrict actin dyna...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Song, Yutong, Zhang, Siyu, Diao, Min, Huang, Shanjin, Li, Sai, Tan, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400672/
https://www.ncbi.nlm.nih.gov/pubmed/32802403
http://dx.doi.org/10.1038/s41421-020-0184-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400672/
https://www.ncbi.nlm.nih.gov/pubmed/32802403
http://dx.doi.org/10.1038/s41421-020-0184-9

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