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PSGL-1 inhibits HIV-1 infection by restricting actin dynamics and sequestering HIV envelope proteins
PSGL-1 has recently been identified as an HIV restriction factor that inhibits HIV DNA synthesis and more potently, virion infectivity. But the underlying mechanisms of these inhibitions are unknown. Here we show that PSGL-1 directly binds to cellular actin filaments (F-actin) to restrict actin dyna...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Singapore
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400672/ https://www.ncbi.nlm.nih.gov/pubmed/32802403 http://dx.doi.org/10.1038/s41421-020-0184-9 |