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A novel protective role of sacubitril/valsartan in cyclophosphamide induced lung injury in rats: impact of miRNA-150-3p on NF-κB/MAPK signaling trajectories

Cyclophosphamide (CP) is a chemotherapeutic agent that induces oxidative stress causing multiple organ damage. Sacubitril/valsartan, is a combined formulation of neprilysin inhibitor (sacubitril) and angiotensin II receptor blocker (valsartan), that induces the protective effect of brain natriuretic...

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Detalles Bibliográficos
Autores principales: Abdel-Latif, Ghada A., Elwahab, Azza H. Abd, Hasan, Rehab A., ElMongy, Noura F., Ramzy, Maggie M., Louka, Manal L., Schaalan, Mona F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400763/
https://www.ncbi.nlm.nih.gov/pubmed/32747644
http://dx.doi.org/10.1038/s41598-020-69810-5