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GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes

The mechanisms mediating suppression of reproduction in response to decreased nutrient availability remain undefined, with studies suggesting regulation occurs within the hypothalamus, pituitary, or gonads. By manipulating glucose utilization and GLUT1 expression in a pituitary gonadotrope cell mode...

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Detalles Bibliográficos
Autores principales: Nicholas, Dequina A., Knight, Vashti S., Tonsfeldt, Karen J., Terasaka, Tomohiro, Molinar-Inglis, Olivia, Stephens, Shannon B. Z., Trejo, JoAnn, Kauffman, Alexander S., Mellon, Pamela L., Lawson, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400764/
https://www.ncbi.nlm.nih.gov/pubmed/32747664
http://dx.doi.org/10.1038/s41598-020-69913-z