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Intracellular and tissue specific expression of FTO protein in pig: changes with age, energy intake and metabolic status
Genome-wide association studies in the FTO gene have identified SNPs correlating with obesity and type 2 diabetes. In mice, lack of Fto function leads to intrauterine growth retardation and lean phenotype, whereas in human it is lethal. The aim of this study in a pig model was to determine the local...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400765/ https://www.ncbi.nlm.nih.gov/pubmed/32747736 http://dx.doi.org/10.1038/s41598-020-69856-5 |