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Clinical and molecular characteristics of Chinese non‐small cell lung cancer patients with ERBB2 transmembrane domain mutations

Transmembrane domain (TMD) mutations of ERBB2 have previously been reported in lung cancer patients in addition to well‐studied kinase domain (KD) mutations, which may stabilize ERBB2 heterodimerization with other EGFR family members and favor a kinase active conformation. However, the frequency and...

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Detalles Bibliográficos
Autores principales: Fan, Yun, Qiu, Jinrong, Yu, Ruoying, Cao, Ran, Chen, Xiaoxi, Ou, Qiuxiang, Wu, Xue, Shao, Yang W., Nagasaka, Misako, Zhang, Jiexia, Ou, Sai‐Hong Ignatius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400783/
https://www.ncbi.nlm.nih.gov/pubmed/32478891
http://dx.doi.org/10.1002/1878-0261.12733