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Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer

Centrosome amplification (CA) is a common phenomenon in cancer, promotes genomic stability and cancer evolution, and has been reported to promote metastasis. CA promotes a stochastic gain/loss of chromosomes during cell division, known as chromosomal instability (CIN). However, it is unclear whether...

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Detalles Bibliográficos
Autores principales: Singh, Ashok, Denu, Ryan A., Wolfe, Serena K., Sperger, Jamie M., Schehr, Jennifer, Witkowsky, Tessa, Esbona, Karla, Chappell, Richard J., Weaver, Beth A., Burkard, Mark E., Lang, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400789/
https://www.ncbi.nlm.nih.gov/pubmed/32255253
http://dx.doi.org/10.1002/1878-0261.12687