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Konjac glucomannan reverses multi-drug resistance of HepG2/5-FU cells by suppressing AKT signaling and increasing p53 expression

The multi-drug resistance (MDR) of cancer cells, including 5-fluorouracil (5-FU) resistance, has been a serious problem for patients with cancer. The present study aimed to investigate the reversal effects of konjac glucomannan on multi-drug resistance of HepG2/5-FU cells. In the present study, MTT...

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Detalles Bibliográficos
Autores principales: Chen, Bin, Xu, Xin, Zheng, Ke, Liu, Ling, Yu, Yijun, Xin, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401006/
https://www.ncbi.nlm.nih.gov/pubmed/32782527
http://dx.doi.org/10.3892/ol.2020.11790