Defective HIV-1 envelope gene promotes the evolution of the infectious strain through recombination in vitro

BACKGROUND: HIV-1 produces defective mutants in the process of reproduction. The significance of the mutants has not been well investigated. METHODS: The plasmids of wild type (HIV-1(NL4–3)) and Env-defective (HIV-1(SG3)(ΔEnv)) HIV-1 were co-transfected into HEK293T cells. The progeny virus was coll...

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Detalles Bibliográficos
Autores principales: Wei, Huamian, Yu, Danwei, Geng, Xiuzhu, He, Yuxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401196/
https://www.ncbi.nlm.nih.gov/pubmed/32753067
http://dx.doi.org/10.1186/s12879-020-05288-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401196/
https://www.ncbi.nlm.nih.gov/pubmed/32753067
http://dx.doi.org/10.1186/s12879-020-05288-w

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