Cargando…
Defective HIV-1 envelope gene promotes the evolution of the infectious strain through recombination in vitro
BACKGROUND: HIV-1 produces defective mutants in the process of reproduction. The significance of the mutants has not been well investigated. METHODS: The plasmids of wild type (HIV-1(NL4–3)) and Env-defective (HIV-1(SG3)(ΔEnv)) HIV-1 were co-transfected into HEK293T cells. The progeny virus was coll...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401196/ https://www.ncbi.nlm.nih.gov/pubmed/32753067 http://dx.doi.org/10.1186/s12879-020-05288-w |