GCH1 variants contribute to the risk and earlier age-at-onset of Parkinson’s disease: a two-cohort case-control study

BACKGROUND: Common and rare variants of guanosine triphosphate cyclohydrolase 1 (GCH1) gene may play important roles in Parkinson’s disease (PD). However, there is a lack of comprehensive analysis of GCH1 genotypes, especially in non-coding regions. The aim of this study was to explore the genetic c...

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Detalles Bibliográficos
Autores principales: Pan, Hong-xu, Zhao, Yu-wen, Mei, Jun-pu, Fang, Zheng-huan, Wang, Yige, Zhou, Xun, Zhou, Yang-jie, Zhang, Rui, Zhang, Kai-lin, Jiang, Li, Zeng, Qian, He, Yan, Wang, Zheng, Liu, Zhen-hua, Xu, Qian, Sun, Qi-ying, Yang, Yang, Hu, Ya-cen, Chen, Ya-se, Du, Juan, Lei, Li-fang, Zhang, Hai-nan, Wang, Chun-yu, Yan, Xin-xiang, Shen, Lu, Jiang, Hong, Tan, Jie-qiong, Li, Jin-chen, Tang, Bei-sha, Guo, Ji-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401216/
https://www.ncbi.nlm.nih.gov/pubmed/32746945
http://dx.doi.org/10.1186/s40035-020-00212-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401216/
https://www.ncbi.nlm.nih.gov/pubmed/32746945
http://dx.doi.org/10.1186/s40035-020-00212-3

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