Curcumin affects ox-LDL-induced IL-6, TNF-α, MCP-1 secretion and cholesterol efflux in THP-1 cells by suppressing the TLR4/NF-κB/miR33a signaling pathway

The aim of the present study was to study the molecular mechanism of how curcumin decreases the formation of ox-LDL induced human monocyte macrophage foam cells, promotes the efflux of cholesterol and reduces the secretion of inflammatory cytokines. In vitro cultured THP-1 cells were induced to beco...

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Detalles Bibliográficos
Autores principales: Zhong, Yi, Liu, Cheng, Feng, Jian, Li, Jia-Fu, Fan, Zhong-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401289/
https://www.ncbi.nlm.nih.gov/pubmed/32782494
http://dx.doi.org/10.3892/etm.2020.8915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401289/
https://www.ncbi.nlm.nih.gov/pubmed/32782494
http://dx.doi.org/10.3892/etm.2020.8915

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