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Curcumin affects ox-LDL-induced IL-6, TNF-α, MCP-1 secretion and cholesterol efflux in THP-1 cells by suppressing the TLR4/NF-κB/miR33a signaling pathway
The aim of the present study was to study the molecular mechanism of how curcumin decreases the formation of ox-LDL induced human monocyte macrophage foam cells, promotes the efflux of cholesterol and reduces the secretion of inflammatory cytokines. In vitro cultured THP-1 cells were induced to beco...
Autores principales: | Zhong, Yi, Liu, Cheng, Feng, Jian, Li, Jia-Fu, Fan, Zhong-Cai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401289/ https://www.ncbi.nlm.nih.gov/pubmed/32782494 http://dx.doi.org/10.3892/etm.2020.8915 |
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