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TGFβ2-Hepcidin Feed-Forward Loop in the Trabecular Meshwork Implicates Iron in Glaucomatous Pathology

PURPOSE: Elevated levels of transforming-growth-factor (TGF)-β2 in the trabecular meshwork (TM) and aqueous humor are associated with primary open-angle glaucoma (POAG). The underlying mechanism includes alteration of extracellular matrix homeostasis through Smad-dependent and independent signaling....

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Detalles Bibliográficos
Autores principales:	Ashok, Ajay, Chaudhary, Suman, Kritikos, Alexander E., Kang, Min H., McDonald, Dallas, Rhee, Douglas J., Singh, Neena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2020
Materias:	Glaucoma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401420/ https://www.ncbi.nlm.nih.gov/pubmed/32182331 http://dx.doi.org/10.1167/iovs.61.3.24

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