Connexin 50-R205G Mutation Perturbs Lens Epithelial Cell Proliferation and Differentiation

PURPOSE: To investigate the underlying mechanisms for how the mouse Cx50-R205G point mutation, a homologue of the human Cx50-R198W mutation that is linked to cataract-microcornea syndrome, affects proper lens growth and fiber cell differentiation to lead to severe lens phenotypes. METHODS: EdU label...

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Detalles Bibliográficos
Autores principales: Tjahjono, Nikki, Xia, Chun-hong, Li, Rachel, Chu, Sarah, Wang, Jessica, Gong, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401428/
https://www.ncbi.nlm.nih.gov/pubmed/32182330
http://dx.doi.org/10.1167/iovs.61.3.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401428/
https://www.ncbi.nlm.nih.gov/pubmed/32182330
http://dx.doi.org/10.1167/iovs.61.3.25

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