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The β(4)-Subunit of the Large-Conductance Potassium Ion Channel K(Ca)1.1 Regulates Outflow Facility in Mice

PURPOSE: The large-conductance calcium-activated potassium channel K(Ca)1.1 (BK(Ca), maxi-K) influences aqueous humor outflow facility, but the contribution of auxiliary β-subunits to K(Ca)1.1 activity in the outflow pathway is unknown. METHODS: Using quantitative polymerase chain reaction, we measu...

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Detalles Bibliográficos
Autores principales: Bertrand, Jacques A., Schicht, Martin, Stamer, W. Daniel, Baker, David, Sherwood, Joseph M., Lütjen-Drecoll, Elke, Selwood, David L., Overby, Darryl R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401454/
https://www.ncbi.nlm.nih.gov/pubmed/32203982
http://dx.doi.org/10.1167/iovs.61.3.41