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Ablation of Mature miR-183 Leads to Retinal Dysfunction in Mice

PURPOSE: The microRNA cluster miR-183C, which includes miR-183 and two other genes, is critical for multiple sensory systems. In mouse retina, removal of this cluster results in photoreceptor defects in polarization, phototransduction, and outer segment elongation. However, the individual roles of t...

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Detalles Bibliográficos
Autores principales: Zhang, Chang-Jun, Xiang, Lue, Chen, Xue-Jiao, Wang, Xiao-Yun, Wu, Kun-Chao, Zhang, Bo-Wen, Chen, De-Fu, Jin, Guang-Hui, Zhang, Hang, Chen, Yu-Chen, Liu, Wei-Qin, Li, Meng-Lan, Ma, Yue, Jin, Zi-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401733/
https://www.ncbi.nlm.nih.gov/pubmed/32176259
http://dx.doi.org/10.1167/iovs.61.3.12