Protrudin-mediated ER–endosome contact sites promote MT1-MMP exocytosis and cell invasion

Cancer cells break tissue barriers by use of small actin-rich membrane protrusions called invadopodia. Complete invadopodia maturation depends on protrusion outgrowth and the targeted delivery of the matrix metalloproteinase MT1-MMP via endosomal transport by mechanisms that are not known. Here, we...

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Detalles Bibliográficos
Autores principales: Pedersen, Nina Marie, Wenzel, Eva Maria, Wang, Ling, Antoine, Sandra, Chavrier, Philippe, Stenmark, Harald, Raiborg, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401796/
https://www.ncbi.nlm.nih.gov/pubmed/32479595
http://dx.doi.org/10.1083/jcb.202003063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401796/
https://www.ncbi.nlm.nih.gov/pubmed/32479595
http://dx.doi.org/10.1083/jcb.202003063

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