Individual kinetochore-fibers locally dissipate force to maintain robust mammalian spindle structure

At cell division, the mammalian kinetochore binds many spindle microtubules that make up the kinetochore-fiber. To segregate chromosomes, the kinetochore-fiber must be dynamic and generate and respond to force. Yet, how it remodels under force remains poorly understood. Kinetochore-fibers cannot be...

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Detalles Bibliográficos
Autores principales: Long, Alexandra F., Suresh, Pooja, Dumont, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401803/
https://www.ncbi.nlm.nih.gov/pubmed/32435797
http://dx.doi.org/10.1083/jcb.201911090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401803/
https://www.ncbi.nlm.nih.gov/pubmed/32435797
http://dx.doi.org/10.1083/jcb.201911090

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