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Individual kinetochore-fibers locally dissipate force to maintain robust mammalian spindle structure
At cell division, the mammalian kinetochore binds many spindle microtubules that make up the kinetochore-fiber. To segregate chromosomes, the kinetochore-fiber must be dynamic and generate and respond to force. Yet, how it remodels under force remains poorly understood. Kinetochore-fibers cannot be...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401803/ https://www.ncbi.nlm.nih.gov/pubmed/32435797 http://dx.doi.org/10.1083/jcb.201911090 |