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Tissue specific requirement of Drosophila Rcd4 for centriole duplication and ciliogenesis

Rcd4 is a poorly characterized Drosophila centriole component whose mammalian counterpart, PPP1R35, is suggested to function in centriole elongation and conversion to centrosomes. Here, we show that rcd4 mutants exhibit fewer centrioles, aberrant mitoses, and reduced basal bodies in sensory organs....

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Detalles Bibliográficos
Autores principales: Panda, Pallavi, Kovacs, Levente, Dzhindzhev, Nikola, Fatalska, Agnieszka, Persico, Veronica, Geymonat, Marco, Riparbelli, Maria Giovanna, Callaini, Giuliano, Glover, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401805/
https://www.ncbi.nlm.nih.gov/pubmed/32543652
http://dx.doi.org/10.1083/jcb.201912154