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Tissue specific requirement of Drosophila Rcd4 for centriole duplication and ciliogenesis
Rcd4 is a poorly characterized Drosophila centriole component whose mammalian counterpart, PPP1R35, is suggested to function in centriole elongation and conversion to centrosomes. Here, we show that rcd4 mutants exhibit fewer centrioles, aberrant mitoses, and reduced basal bodies in sensory organs....
Autores principales: | Panda, Pallavi, Kovacs, Levente, Dzhindzhev, Nikola, Fatalska, Agnieszka, Persico, Veronica, Geymonat, Marco, Riparbelli, Maria Giovanna, Callaini, Giuliano, Glover, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401805/ https://www.ncbi.nlm.nih.gov/pubmed/32543652 http://dx.doi.org/10.1083/jcb.201912154 |
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