Cargando…

Giant ankyrin-B suppresses stochastic collateral axon branching through direct interaction with microtubules

Giant ankyrin-B (gAnkB) is a 440-kD neurospecific ankyrin-B isoform and a high-confidence target for autism mutations. gAnkB suppresses axon branching through coordination of cortical microtubules, and autism-related mutation of gAnkB results in ectopic neuronal connectivity. We identified a biparti...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Keyu, Yang, Rui, Li, Yubing, Zhou, Jin Chuan, Zhang, Mingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401806/
https://www.ncbi.nlm.nih.gov/pubmed/32640013
http://dx.doi.org/10.1083/jcb.201910053