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Nucleobindin-1 regulates ECM degradation by promoting intra-Golgi trafficking of MMPs

Matrix metalloproteinases (MMPs) degrade several ECM components and are crucial modulators of cell invasion and tissue organization. Although much has been reported about their function in remodeling ECM in health and disease, their trafficking across the Golgi apparatus remains poorly understood. H...

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Detalles Bibliográficos
Autores principales: Pacheco-Fernandez, Natalia, Pakdel, Mehrshad, Blank, Birgit, Sanchez-Gonzalez, Ismael, Weber, Kathrin, Tran, Mai Ly, Hecht, Tobias Karl-Heinz, Gautsch, Renate, Beck, Gisela, Perez, Franck, Hausser, Angelika, Linder, Stefan, von Blume, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401813/
https://www.ncbi.nlm.nih.gov/pubmed/32479594
http://dx.doi.org/10.1083/jcb.201907058