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Endothelial Yes-Associated Protein 1 Promotes Astrocyte Proliferation and Maturation via Cytoplasmic Leukemia Inhibitory Factor Secretion in Oxygen-Induced Retinopathy

PURPOSE: Purpose The role of endothelial Yes-associated protein 1 (YAP) in the pathogenesis of retinal angiogenesis and the astrocyte network in the mouse oxygen-induced retinopathy (OIR) model is unknown. METHODS: For in vivo studies, OIR was induced in conditional endothelial YAP knockout mice and...

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Detalles Bibliográficos
Autores principales: Ai, Li-Qian-Yu, Zhu, Jing-Yi, Chen, Xi, Li, Xue, Luo, Lin-Lin, Hu, Qiu-Mei, Lin, Sen, Ye, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401846/
https://www.ncbi.nlm.nih.gov/pubmed/32271890
http://dx.doi.org/10.1167/iovs.61.4.1