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Lycopene attenuates high glucose-mediated apoptosis in MPC5 podocytes by promoting autophagy via the PI3K/AKT signaling pathway

Podocyte injury serves an important role during the progression of diabetic nephropathy (DN), and lycopene (Lyc) may display a potential protective effect against DN progression. The effects of Lyc on high glucose (HG)-induced podocyte apoptosis and the underlying mechanisms are not completely under...

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Detalles Bibliográficos
Autores principales: Wang, Qingfen, Li, Rui, Xiao, Zhi, Hou, Cun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401945/
https://www.ncbi.nlm.nih.gov/pubmed/32765784
http://dx.doi.org/10.3892/etm.2020.8999