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Honokiol Reduces Fungal Load, Toll-Like Receptor-2, and Inflammatory Cytokines in Aspergillus fumigatus Keratitis

PURPOSE: We characterized the effects of Honokiol (HNK) on Aspergillus fumigatus–caused keratomycosis and the underlying mechanisms. HNK is known to have anti-inflammatory and antifungal properties, but the influence on fungal keratitis (FK) remains unknown. METHODS: In ex vivo, minimum inhibitory c...

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Detalles Bibliográficos
Autores principales: Zhan, Lu, Peng, Xudong, Lin, Jing, Zhang, Yingxue, Gao, Han, Zhu, Yunan, Huan, Yu, Zhao, Guiqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401949/
https://www.ncbi.nlm.nih.gov/pubmed/32347916
http://dx.doi.org/10.1167/iovs.61.4.48