SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors

The spike (S) glycoprotein in the envelope of SARS-CoV-2 is densely glycosylated but the functions of its glycosylation are unknown. Here we demonstrate that S is recognized in a glycan-dependent manner by multiple innate immune receptors including the mannose receptor MR/CD206, DC-SIGN/CD209, L-SIG...

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Detalles Bibliográficos
Autores principales: Gao, Chao, Zeng, Junwei, Jia, Nan, Stavenhagen, Kathrin, Matsumoto, Yasuyuki, Zhang, Hua, Li, Jiang, Hume, Adam J., Mühlberger, Elke, van Die, Irma, Kwan, Julian, Tantisira, Kelan, Emili, Andrew, Cummings, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402034/
https://www.ncbi.nlm.nih.gov/pubmed/32766577
http://dx.doi.org/10.1101/2020.07.29.227462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402034/
https://www.ncbi.nlm.nih.gov/pubmed/32766577
http://dx.doi.org/10.1101/2020.07.29.227462

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