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Inhibition of HDAC6 Attenuates Diabetes-Induced Retinal Redox Imbalance and Microangiopathy

We investigated the contributing role of the histone deacetylase 6 (HDAC6) to the early stages of diabetic retinopathy (DR). Furthermore, we examined the mechanism of action of HDAC6 in human retinal endothelial cells (HuREC) exposed to glucidic stress. Streptozotocin-induced diabetic rats (STZ-rats...

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Detalles Bibliográficos
Autores principales: Abouhish, Hossameldin, Thounaojam, Menaka C., Jadeja, Ravirajsinh N., Gutsaeva, Diana R., Powell, Folami L., Khriza, Mohamed, Martin, Pamela M., Bartoli, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402090/
https://www.ncbi.nlm.nih.gov/pubmed/32660051
http://dx.doi.org/10.3390/antiox9070599