Dauricine Protects from LPS-Induced Bone Loss via the ROS/PP2A/NF-κB Axis in Osteoclasts

Dauricine (DAC), an isoquinoline alkaloid, exhibits anti-inflammatory activity. We hypothesized that DAC may prevent the inflammatory bone loss induced by lipopolysaccharide (LPS). LPS-induced bone loss was decreased by DAC in female C57BL/6J mice as evaluated by micro-computerized tomography (μCT)...

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Detalles Bibliográficos
Autores principales: Park, Hyun-Jung, Gholam Zadeh, Malihatosadat, Suh, Jae-Hee, Choi, Hye-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402093/
https://www.ncbi.nlm.nih.gov/pubmed/32640590
http://dx.doi.org/10.3390/antiox9070588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402093/
https://www.ncbi.nlm.nih.gov/pubmed/32640590
http://dx.doi.org/10.3390/antiox9070588

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