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Glutathione S-Transferase Rescues Motor Neuronal Toxicity in Fly Model of Amyotrophic Lateral Sclerosis

Transactive response DNA-binding protein-43 (TDP-43) is involved in the pathology of familial and sporadic amyotrophic lateral sclerosis (ALS). TDP-43-mediated ALS models in mice, Drosophila melanogaster, and zebrafish exhibit dysfunction of locomotor function, defective neuromuscular junctions, and...

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Detalles Bibliográficos
Autores principales: Cha, Sun Joo, Han, Yeo Jeong, Choi, Hyun-Jun, Kim, Hyung-Jun, Kim, Kiyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402175/
https://www.ncbi.nlm.nih.gov/pubmed/32674363
http://dx.doi.org/10.3390/antiox9070615