Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions

Dual leucine zipper kinase (DLK, Map3k12) is an axonal protein that governs the balance between degeneration and regeneration through its downstream effectors c-jun N-terminal kinase (JNK) and phosphorylated c-jun (p-c-Jun). In peripheral nerves DLK is generally inactive until induced by injury, aft...

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Detalles Bibliográficos
Autores principales: Goodwani, Sunil, Fernandez, Celia, Acton, Paul J., Buggia-Prevot, Virginie, McReynolds, Morgan L., Ma, Jiacheng, Hu, Cheng Hui, Hamby, Mary E., Jiang, Yongying, Le, Kang, Soth, Michael J., Jones, Philip, Ray, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402291/
https://www.ncbi.nlm.nih.gov/pubmed/32659913
http://dx.doi.org/10.3390/ijms21144849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402291/
https://www.ncbi.nlm.nih.gov/pubmed/32659913
http://dx.doi.org/10.3390/ijms21144849

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