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Chaetocin Improves Pig Cloning Efficiency by Enhancing Epigenetic Reprogramming and Autophagic Activity

Efficient epigenetic reprogramming is crucial for the in vitro development of mammalian somatic cell nuclear transfer (SCNT) embryos. The aberrant levels of histone H3 lysine 9 trimethylation (H3K9me3) is an epigenetic barrier. In this study, we evaluated the effects of chaetocin, an H3K9me3-specifi...

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Detalles Bibliográficos
Autores principales: Jeong, Pil-Soo, Sim, Bo-Woong, Park, Soo-Hyun, Kim, Min Ju, Kang, Hyo-Gu, Nanjidsuren, Tsevelmaa, Lee, Sanghoon, Song, Bong-Seok, Koo, Deog-Bon, Kim, Sun-Uk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402317/
https://www.ncbi.nlm.nih.gov/pubmed/32650566
http://dx.doi.org/10.3390/ijms21144836