Cargando…

Chaetocin Improves Pig Cloning Efficiency by Enhancing Epigenetic Reprogramming and Autophagic Activity

Efficient epigenetic reprogramming is crucial for the in vitro development of mammalian somatic cell nuclear transfer (SCNT) embryos. The aberrant levels of histone H3 lysine 9 trimethylation (H3K9me3) is an epigenetic barrier. In this study, we evaluated the effects of chaetocin, an H3K9me3-specifi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeong, Pil-Soo, Sim, Bo-Woong, Park, Soo-Hyun, Kim, Min Ju, Kang, Hyo-Gu, Nanjidsuren, Tsevelmaa, Lee, Sanghoon, Song, Bong-Seok, Koo, Deog-Bon, Kim, Sun-Uk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402317/ https://www.ncbi.nlm.nih.gov/pubmed/32650566 http://dx.doi.org/10.3390/ijms21144836

Ejemplares similares

Combined Chaetocin/Trichostatin A Treatment Improves the Epigenetic Modification and Developmental Competence of Porcine Somatic Cell Nuclear Transfer Embryos
por: Jeong, Pil-Soo, et al.
Publicado: (2021)

Butylparaben Is Toxic to Porcine Oocyte Maturation and Subsequent Embryonic Development Following In Vitro Fertilization
por: Jeong, Pil-Soo, et al.
Publicado: (2020)

Effect of Oocyte Quality Assessed by Brilliant Cresyl Blue (BCB) Staining on Cumulus Cell Expansion and Sonic Hedgehog Signaling in Porcine during In Vitro Maturation
por: Lee, Sanghoon, et al.
Publicado: (2020)

Luteolin supplementation during porcine oocyte maturation improves the developmental competence of parthenogenetic activation and cloned embryos
por: Jeong, Pil-Soo, et al.
Publicado: (2023)

Embryo aggregation regulates in vitro stress conditions to promote developmental competence in pigs
por: Jeong, Pil-Soo, et al.
Publicado: (2019)

The transcription factor Ap-1 regulates monkey 20α-hydroxysteroid dehydrogenase promoter activity in CHO cells
por: Nanjidsuren, Tsevelmaa, et al.
Publicado: (2014)

Restoration of Developmental Competence in Low-Quality Porcine Cumulus–Oocyte Complexes through the Supplementation of Sonic Hedgehog Protein during In Vitro Maturation
por: Jeong, Pil-Soo, et al.
Publicado: (2023)

Effect of Triclosan Exposure on Developmental Competence in Parthenogenetic Porcine Embryo during Preimplantation
por: Kim, Min Ju, et al.
Publicado: (2020)

Mdivi-1, mitochondrial fission inhibitor, impairs developmental competence and mitochondrial function of embryos and cells in pigs
por: YEON, Ji-Yeong, et al.
Publicado: (2014)

The anticancer effect of chaetocin is enhanced by inhibition of autophagy
por: Jung, H-J, et al.
Publicado: (2016)

Luteolin Orchestrates Porcine Oocyte Meiotic Progression by Maintaining Organelle Dynamics Under Oxidative Stress
por: Park, Soo-Hyun, et al.
Publicado: (2021)

Lycopene Improves In Vitro Development of Porcine Embryos by Reducing Oxidative Stress and Apoptosis
por: Kang, Hyo-Gu, et al.
Publicado: (2021)

Exposure of Triclosan in Porcine Oocyte Leads to Superoxide Production and Mitochondrial-Mediated Apoptosis during In Vitro Maturation
por: Park, Hyo-Jin, et al.
Publicado: (2020)

Improved Therapeutic Effect against Leukemia by a Combination of the Histone Methyltransferase Inhibitor Chaetocin and the Histone Deacetylase Inhibitor Trichostatin A
por: Tran, Huong Thi Thanh, et al.
Publicado: (2013)

The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma
por: Ozyerli-Goknar, Ezgi, et al.
Publicado: (2019)

Epigenetic reprogramming in the mammalian embryo: struggle of the clones
por: Mann, Mellissa RW, et al.
Publicado: (2002)

Nucleologenesis and embryonic genome activation are defective in interspecies cloned embryos between bovine ooplasm and rhesus monkey somatic cells
por: Song, Bong-Seok, et al.
Publicado: (2009)

Anethole improves the developmental competence of porcine embryos by reducing oxidative stress via the sonic hedgehog signaling pathway
por: Joo, Ye Eun, et al.
Publicado: (2023)

Effect of chaetocin on renal cell carcinoma cells and cytokine-induced killer cells
por: Rombo, Roman, et al.
Publicado: (2016)

Enhancement of porcine in vitro embryonic development through luteolin-mediated activation of the Nrf2/Keap1 signaling pathway
por: Jeon, Se-Been, et al.
Publicado: (2023)

Autophagic reprogramming of bone marrow–derived macrophages
por: Mazher, Mayada, et al.
Publicado: (2022)

Identification of epipolythiodioxopiperazines HDN-1 and chaetocin as novel inhibitor of heat shock protein 90
por: Song, Xiaoping, et al.
Publicado: (2015)

Ganglioside GD1a promotes oocyte maturation, furthers preimplantation development, and increases blastocyst quality in pigs
por: KIM, Jin-Woo, et al.
Publicado: (2016)

Approaches used to improve epigenetic reprogramming in buffalo cloned embryos
por: Saini, Monika, et al.
Publicado: (2018)

Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer
por: Liao, Xinwen, et al.
Publicado: (2019)

Chaetocin exhibits anticancer effects in esophageal squamous cell carcinoma via activation of Hippo pathway
por: Li, Lin, et al.
Publicado: (2023)

Chaetocin enhances dendritic cell function via the induction of heat shock protein and cancer testis antigens in myeloma cells
por: Vo, Manh-Cuong, et al.
Publicado: (2017)

Production of Cloned Korean Native Pig by Somatic Cell Nuclear Transfer
por: Hwang, In-Sul, et al.
Publicado: (2015)

The anticancer effects of chaetocin are independent of programmed cell death and hypoxia, and are associated with inhibition of endothelial cell proliferation
por: Isham, C R, et al.
Publicado: (2012)

Chaetocin induces caspase-dependent apoptosis in ovarian cancer cells via the generation of reactive oxygen species
por: Li, Zhongjun, et al.
Publicado: (2019)

Chaetocin Promotes Osteogenic Differentiation via Modulating Wnt/Beta-Catenin Signaling in Mesenchymal Stem Cells
por: Liang, Youde, et al.
Publicado: (2021)

Peroxiredoxin 1 Controls Ovulation and Ovulated Cumulus–Oocyte Complex Activity through TLR4-Derived ERK1/2 Signaling in Mice
por: Park, Hyo-Jin, et al.
Publicado: (2021)

The SUV39H1 inhibitor chaetocin induces differentiation and shows synergistic cytotoxicity with other epigenetic drugs in acute myeloid leukemia cells
por: Lai, Y-S, et al.
Publicado: (2015)

Cardiovascular Regeneration via Stem Cells and Direct Reprogramming: A Review
por: Lee, Choon-Soo, et al.
Publicado: (2022)

Suberoylanilide hydroxamic acid during in vitro culture improves development of dog-pig interspecies cloned embryos but not dog cloned embryos
por: KIM, Min Jung, et al.
Publicado: (2018)

Stress-responsive Gdf15 counteracts renointestinal toxicity via autophagic and microbiota reprogramming
por: Ray, Navin, et al.
Publicado: (2023)

Aberrant Expression of TIMP-2 and PBEF Genes in the Placentae of Cloned Mice Due to Epigenetic Reprogramming Error
por: Kim, Hong Rye, et al.
Publicado: (2016)

Epigenetic Modification Agents Improve Genomic Methylation Reprogramming in Porcine Cloned Embryos
por: HUAN, Yan Jun, et al.
Publicado: (2014)

Treatment With Glycogen Synthase Kinase 3β Inhibitor Decreases Apoptotic and Autophagic Reactions in Rat Rotator Cuff Tears
por: Kim, Yang-Soo, et al.
Publicado: (2021)

Human leukocytes regulate ganglioside expression in cultured micro-pig aortic endothelial cells
por: Cho, Jin-Hyoung, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2fmk10lpov1qgrv81o1a4gro8h