SOX2 and p53 Expression Control Converges in PI3K/AKT Signaling with Versatile Implications for Stemness and Cancer

Stemness and reprogramming involve transcriptional master regulators that suppress cell differentiation while promoting self-renewal. A distinguished example thereof is SOX2, a high mobility group (HMG)-box transcription factor (TF), whose subcellular localization and turnover regulation in embryoni...

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Detalles Bibliográficos
Autores principales: Schaefer, Thorsten, Steiner, Rebekah, Lengerke, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402325/
https://www.ncbi.nlm.nih.gov/pubmed/32664542
http://dx.doi.org/10.3390/ijms21144902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402325/
https://www.ncbi.nlm.nih.gov/pubmed/32664542
http://dx.doi.org/10.3390/ijms21144902

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