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SOX2 and p53 Expression Control Converges in PI3K/AKT Signaling with Versatile Implications for Stemness and Cancer

Stemness and reprogramming involve transcriptional master regulators that suppress cell differentiation while promoting self-renewal. A distinguished example thereof is SOX2, a high mobility group (HMG)-box transcription factor (TF), whose subcellular localization and turnover regulation in embryoni...

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Detalles Bibliográficos
Autores principales:	Schaefer, Thorsten, Steiner, Rebekah, Lengerke, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402325/ https://www.ncbi.nlm.nih.gov/pubmed/32664542 http://dx.doi.org/10.3390/ijms21144902

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