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Intracellular Toxic Advanced Glycation End-Products Promote the Production of Reactive Oxygen Species in HepG2 Cells

Hepatocyte cell death is a key process in the pathogenesis of nonalcoholic steatohepatitis (NASH). However, the factors responsible for and mechanisms underlying NASH-related cell death have not yet been elucidated in detail. We herein investigated the effects of intracellular glyceraldehyde (GA)-de...

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Detalles Bibliográficos
Autores principales: Sakasai-Sakai, Akiko, Takata, Takanobu, Takeuchi, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402329/
https://www.ncbi.nlm.nih.gov/pubmed/32660150
http://dx.doi.org/10.3390/ijms21144861