Cargando…

Intracellular Toxic Advanced Glycation End-Products Promote the Production of Reactive Oxygen Species in HepG2 Cells

Hepatocyte cell death is a key process in the pathogenesis of nonalcoholic steatohepatitis (NASH). However, the factors responsible for and mechanisms underlying NASH-related cell death have not yet been elucidated in detail. We herein investigated the effects of intracellular glyceraldehyde (GA)-de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sakasai-Sakai, Akiko, Takata, Takanobu, Takeuchi, Masayoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402329/ https://www.ncbi.nlm.nih.gov/pubmed/32660150 http://dx.doi.org/10.3390/ijms21144861

Ejemplares similares

Impact of intracellular toxic advanced glycation end-products (TAGE) on murine myoblast cell death
por: Takata, Takanobu, et al.
Publicado: (2020)

Intracellular Toxic Advanced Glycation End-Products May Induce Cell Death and Suppress Cardiac Fibroblasts
por: Takata, Takanobu, et al.
Publicado: (2022)

Intracellular toxic advanced glycation end-products in cardiomyocytes may cause cardiovascular disease
por: Takata, Takanobu, et al.
Publicado: (2019)

Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver
por: Takata, Takanobu, et al.
Publicado: (2019)

Impact of intracellular glyceraldehyde-derived advanced glycation end-products on human hepatocyte cell death
por: Sakasai-Sakai, Akiko, et al.
Publicado: (2017)

Intracellular Toxic Advanced Glycation End-Products in 1.4E7 Cell Line Induce Death with Reduction of Microtubule-Associated Protein 1 Light Chain 3 and p62
por: Takata, Takanobu, et al.
Publicado: (2022)

The Association between Accumulation of Toxic Advanced Glycation End-Products and Cytotoxic Effect in MC3T3-E1 Cells
por: Sakasai-Sakai, Akiko, et al.
Publicado: (2022)

Generation of glyceraldehyde-derived advanced glycation end-products in pancreatic cancer cells and the potential of tumor promotion
por: Takata, Takanobu, et al.
Publicado: (2017)

Immunological evidence for in vivo production of novel advanced glycation end-products from 1,5-anhydro-D-fructose, a glycogen metabolite
por: Sakasai-Sakai, Akiko, et al.
Publicado: (2019)

Serum levels of 1,5-anhydroglucitol and 1,5-anhydrofructose-derived advanced glycation end products in patients undergoing hemodialysis
por: Tanaka, Kenji, et al.
Publicado: (2021)

The Relevance of Toxic AGEs (TAGE) Cytotoxicity to NASH Pathogenesis: A Mini-Review
por: Sakasai-Sakai, Akiko, et al.
Publicado: (2019)

Effects of Toxic AGEs (TAGE) on Human Health
por: Takeuchi, Masayoshi, et al.
Publicado: (2022)

Toxic AGE (TAGE) Theory for the Pathophysiology of the Onset/Progression of NAFLD and ALD
por: Takeuchi, Masayoshi, et al.
Publicado: (2017)

Is the Novel Slot Blot a Useful Method for Quantification of Intracellular Advanced Glycation End-Products?
por: Takata, Takanobu
Publicado: (2023)

Potential of an Interorgan Network Mediated by Toxic Advanced Glycation End-Products in a Rat Model
por: Inoue, Shinya, et al.
Publicado: (2020)

Intracellular Toxic AGEs (TAGE) Triggers Numerous Types of Cell Damage
por: Takeuchi, Masayoshi, et al.
Publicado: (2021)

Involvement of Intracellular TAGE and the TAGE–RAGE–ROS Axis in the Onset and Progression of NAFLD/NASH
por: Sakasai-Sakai, Akiko, et al.
Publicado: (2023)

Toxicity of advanced glycation end products (Review)
por: Kuzan, Aleksandra
Publicado: (2021)

Cancer Malignancy Is Enhanced by Glyceraldehyde-Derived Advanced Glycation End-Products
por: Takino, Jun-Ichi, et al.
Publicado: (2010)

Novel In Vitro Assay of the Effects of Kampo Medicines against Intra/Extracellular Advanced Glycation End-Products in Oral, Esophageal, and Gastric Epithelial Cells
por: Takata, Takanobu, et al.
Publicado: (2023)

Neuropathy induced by exogenously administered advanced glycation end‐products in rats
por: Nishizawa, Yusuke, et al.
Publicado: (2010)

Pyridoxamine and Aminoguanidine Attenuate the Abnormal Aggregation of β-Tubulin and Suppression of Neurite Outgrowth by Glyceraldehyde-Derived Toxic Advanced Glycation End-Products
por: Ooi, Hayahide, et al.
Publicado: (2022)

Alyssin and Iberin in Cruciferous Vegetables Exert Anticancer Activity in HepG2 by Increasing Intracellular Reactive Oxygen Species and Tubulin Depolymerization
por: Pocasap, Piman, et al.
Publicado: (2019)

Advanced glycation end products reduce the calcium transient in cardiomyocytes by increasing production of reactive oxygen species and nitric oxide
por: Hegab, Zeinab, et al.
Publicado: (2017)

Acetaldehyde-Derived Advanced Glycation End-Products Promote Alcoholic Liver Disease
por: Hayashi, Nobuhiko, et al.
Publicado: (2013)

RasGRP2 inhibits glyceraldehyde-derived toxic advanced glycation end-products from inducing permeability in vascular endothelial cells
por: Takino, Jun-ichi, et al.
Publicado: (2021)

Reactive oxygen species inhibits Listeria monocytogenes invasion into HepG2 epithelial cells
por: Chen, Guo‐wei, et al.
Publicado: (2018)

Glyceraldehyde-Derived Advanced Glycation End Products Accumulate Faster Than N(ε)-(Carboxymethyl) Lysine
por: Yokota, Mami, et al.
Publicado: (2017)

Assessment of the Concentrations of Various Advanced Glycation End-Products in Beverages and Foods That Are Commonly Consumed in Japan
por: Takeuchi, Masayoshi, et al.
Publicado: (2015)

Hyperglycemia-Induced Reactive Oxygen Species Increase Expression of the Receptor for Advanced Glycation End Products (RAGE) and RAGE Ligands
por: Yao, Dachun, et al.
Publicado: (2010)

Intracellular distribution pattern of procalcitonin in human monocytes and HepG2 cells
por: Ruβwurm, S, et al.
Publicado: (1999)

Advanced Glycation End Products and Psoriasis
por: Maurelli, Martina, et al.
Publicado: (2023)

Diosgenin Induces Apoptosis in HepG2 Cells through Generation of Reactive Oxygen Species and Mitochondrial Pathway
por: Kim, Dae Sung, et al.
Publicado: (2012)

Advanced glycation end products and cognitive impairment in schizophrenia
por: Kobori, Akiko, et al.
Publicado: (2021)

High complexity of toxic reactions: parallels between products of oxidative stress and advanced glycation end products
por: Bolt, Hermann M.
Publicado: (2020)

Glucose availability determines silver nanoparticles toxicity in HepG2
por: Zuberek, Mariusz, et al.
Publicado: (2015)

Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells
por: Grünig, David, et al.
Publicado: (2018)

Insulin resistance is an independent correlate of high serum levels of advanced glycation end products (AGEs) and low testosterone in non-diabetic men
por: Tahara, Nobuhiro, et al.
Publicado: (2010)

Reactive Oxygen Species Induces Lipid Droplet Accumulation in HepG2 Cells by Increasing Perilipin 2 Expression
por: Jin, Yi, et al.
Publicado: (2018)

Dietary Advanced Glycation End Products and Aging
por: Luevano-Contreras, Claudia, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_jmheqlq1tln1aeura7qbojukgs