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The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function

Hepatic ischemia/reperfusion (I/R) injury is a leading cause of organ dysfunction and failure in numerous pathological and surgical settings. At the core of this issue lies mitochondrial dysfunction. Hence, strategies that prime mitochondria towards damage resilience might prove applicable in a clin...

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Detalles Bibliográficos
Autores principales: Teodoro, João S., Amorim, João A., Machado, Ivo F., Castela, Ana C., Steegborn, Clemens, Sinclair, David A., Rolo, Anabela P., Palmeira, Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402335/
https://www.ncbi.nlm.nih.gov/pubmed/32664470
http://dx.doi.org/10.3390/ijms21144896