Protein phosphatase 1 catalyzes HBV core protein dephosphorylation and is co-packaged with viral pregenomic RNA into nucleocapsids

Hepatitis B virus (HBV) replicates its genomic DNA via viral DNA polymerase self-primed reverse transcription of a RNA pre-genome in the nucleocapsid assembled by 120 core protein (Cp) dimers. The arginine-rich carboxyl-terminal domain (CTD) of Cp plays an important role in the selective packaging o...

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Detalles Bibliográficos
Autores principales: Hu, Zhanying, Ban, Haiqun, Zheng, Haiyan, Liu, Mingliang, Chang, Jinhong, Guo, Ju-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402523/
https://www.ncbi.nlm.nih.gov/pubmed/32702076
http://dx.doi.org/10.1371/journal.ppat.1008669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402523/
https://www.ncbi.nlm.nih.gov/pubmed/32702076
http://dx.doi.org/10.1371/journal.ppat.1008669

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