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Protein phosphatase 1 catalyzes HBV core protein dephosphorylation and is co-packaged with viral pregenomic RNA into nucleocapsids
Hepatitis B virus (HBV) replicates its genomic DNA via viral DNA polymerase self-primed reverse transcription of a RNA pre-genome in the nucleocapsid assembled by 120 core protein (Cp) dimers. The arginine-rich carboxyl-terminal domain (CTD) of Cp plays an important role in the selective packaging o...
Autores principales: | Hu, Zhanying, Ban, Haiqun, Zheng, Haiyan, Liu, Mingliang, Chang, Jinhong, Guo, Ju-Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402523/ https://www.ncbi.nlm.nih.gov/pubmed/32702076 http://dx.doi.org/10.1371/journal.ppat.1008669 |
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